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Y-Chromosome Microdeletions And Recurrent Pregnancy Losses

Y-Chromosome Microdeletions And Recurrent Pregnancy LossDewan and colleagues conducted a study which demonstrated that the prevalence of y-chromosome microdeletions was higher in patients(couples) undergoing evaluation for recurrent pregnancy loss (n=17) compared to 18 fertile couples without pregnancy loss and 10 infertile men. 

Eighty-two (82%) percent of the men from the couples with recurrent pregnancy loss as compared to 0% in the normally fertile males and 20% in the infertile males were found to have microdeletions in the AZFc region of the Y chromosome.

 

Referance: Dewan S, Puscheck EE. et all. Y-chromosome microdeletions and recurrent pregnancy loss. Fertil Steril. 2006;
85(2):441-5.

 

 

Last Updated on Tuesday, 17 November 2009 20:24